Fluorescent and Colorimetric DNA and Protein Microarray Platforms

Arrayit Fluorescent and Colorimetric DNA and Protein Microarray Platforms provide powerful and affordable solutions for DNA and protein microarray life sciences research in your laboratory. Each platform is configured on a custom basis to create the platform best-suited for customer needs and include the microarray instruments, tools and reagents required for fluorescence-based DNA and protein microarrays. The list price shown is an average price based on turnkey manufacturing and scanning. Prices will be higher for enterprise-level solutions. We also offer much more affordable systems for researchers based on preowned equipment. Please contact our sales team (arrayit@arrayit.com) for exact pricing and lead times.

Instruments - Microarray Platforms - Fluorescent and Colorimetric DNA and Protein Microarray Platforms

Arrayit offers the advanced and affordable platforms for fluorescent and colorimetric DNA and protein microarray experimentation including personal and enterprise level microarray printers and scanners as well as the tools, kits and reagents required to manufacture and deploy DNA and protein microarrays in your lab. Arrayit offers excellent turnkey solutions a wide variety of fluorescent microarray applications.

Table of Contents

• Introduction
• Platform Components
• Ordering Information
• Warranty

Introduction
Arrayit Fluorescent and Colorimetric DNA and Protein Microarray Platforms empower customers with advanced solutions for miniaturized and multiplexed microarray assays. Miniaturizing and multiplexing traditional laboratory assays reduces cost and increases the accuracy of the assays. When multiple analytes are processed in a microarray format, each analyte that binds to a capture agent on the surface of the microarray is subjected to exactly the same reaction and processing conditions, rather than each analyte being reacted in a separate well for example. This reduces variability when multiple samples are analyzed. Additionally, the microarray format uses much lower target and probe volumes, which increase the concentration of molecules in solution as well as the capture agents on the surface. Higher concentrations mean greater detectivity and sensitivity and faster processing times. Microarray formats are much less expensive than traditional assays because they reduce expensive reagent consumption. Arrayit foresees that microarray assays will replace all traditional macroscopic assays over time based on cost considerations alone. Arrayit custom platforms are capable of performing a multitude of assays including:

• cDNA-fluorescent cDNA
• oligonucleotide-fluorescent cDNA
• oligonucleotide-fluorescent genomic DNA
• enzyme-linked immunosorptive assay (ELISA)
• protein-protein
• protein-drug
• antibody-antigen
• antigen-antibody
• protein-DNA
• protein-RNA
• protein-carbohydrate

Figure 1. SpotBot® 4 Protein Edition Personal Microarrayer with cooled platen and chiller bath, enabling desktop protein microarray manufacturing.

Figure 2. SpotLight™ 2 Two-Color Fluorescence Microarray Scanner with Cy3™ and Cy5™ detection and 10 µm scan resolution for desktop fluorescent protein microarray scanning.

Arrayit Platform Components
Arrayit DNA and Protein Microarray Platforms include everything required to perform robust DNA and protein microarray experiments in your laboratory. Arrayit platforms includes:

Microarray Printers including microarrayers with cold room capabilities built in and delivering sub-nanoliter volumes of sample to DNA and protein microarray slides using microarray printing devices. Arrayit microarray printers are capable of printing thousands of samples on glass slides for highly miniaturized and multiplexed assays. For high-throughput laboratories including core facilities and biotech companies, platforms can include NanoPrint™ 2 microarrayers.

Microarray Scanners including personal and enterprise scale microarray scanning instruments that produce high-resolution scanned images of fluorescent and colorimetric microarray assays.

Bioinformatics Computers including powerful desktop personal computer (PC) configurations capable of running platform instruments and analysis software at high speeds.

Microarray Slides including 1 x 25 x 76 mm glass and membrane slides for a wide diversity of microarray assays including epoxy, aldehyde, amine, nitrocellulose, mirror and other surfaces for high signal strength and low background when used in conjunction with platform components.

Microarray Buffers and Solutions for all aspects of the microarray lifecycle including buffers and solutions for printing, blocking, reacting, washing and rinsing. Arrayit buffers, developed over decades of research and development are formulated to provide superior assay performance and speed at affordable prices.

Microarray Hybridization Cassettes provide convenient and affordable hardware tools for microarray assays including single slide, multiple slide and multi-well formats supporting both cover slip and hybridization station-based solution assays.

Microarray Hybridization Stations that support DNA and protein microarray assays based on multi-well hybridization cassettes. Microarray hybridization stations provide temperature-controlled mixing for added speed and precision in DNA and protein microarray experimentation.

Microarray Wash Trays and Wash Stations provide affordable solutions for slide-based DNA and protein microarray blocking and washing.

Microarray Centrifuges provide affordable benchtop instruments for microarray slide drying following the blocking, wash and rinse steps as dictated by a given assay.

Figure 3. Arrayit Bioinformatics Mini Computer with the latest commputer hardware and software for high-speed analysis of microarray data in a highly compact computer footprint.

Figure 4. Fluorescent protein microarray scanned at 10 µm scan resolution with the SpotLight™ Two-Color Fluorescence Microarray Scanner. Strong signals and low background permit high detectivity and dynamic range for a wide range of DNA and protein microarray assays.

Figure 5. Arrayit NanoPrint™ 2 LM60 Enterprise Scale Microarray Printer featuring linear encoders and advanced automation for high-throughput manufacturing customers.

Figure 6. Arrayit GeneMachines OmniGrid Accent Microarray Printer for customers seeking high-quality refurbished instruments as a cost-savings measure.

Figure 7. Arrayit Hybridization Cassettes for laboratories seeking to deploy single slide DNA and protein microarray assays based commercial or custom microarray slide content.

Figure 8. Arrayit SuperEpoxy 2 Microarray Substrate Slides for DNA and protein microarray customers seeking to deploy 1 x 25 x 76 mm glass slide formats using Arrayit's widely-published epoxide slide chemistry.